KLH in Clinical Trials

Clinical trials involving KLH. Details such as study status, design and investigators are available by link to outside sites.

Clinical trial links are intended for informational purposes only, and are not solicitations for any study nor provided for the purposes of giving medical advice. See Terms of Use for this site.

(in order by date)

Monday
Jan302017

2017-000084-32

Tuesday
Nov292016

NCT02980198

Wednesday
Oct122016

NCT02947854

Study to Assess Safety, Tolerability and Immune Response of Fimaporfin-induced Photochemical Internalisation of Antigen/Adjuvant

An Open-label, Phase I/Proof of Principle, Dose Escalation Study to Assess Safety, Tolerability and Immune Response of Fimaporfin-induced Photochemical Internalisation (PCI) of Antigen/Adjuvant in Healthy Male/Female Subjects

Condition: Healthy Volunteers
Sponsor: PCI Biotech
Phase 1 


Friday
May202016

NCT02800811

Safety, Tolerability, PK, PD, and Immunogenicity of Single and Multiple Ascending Intravenous Doses of FR104

First-in-human, phase I, randomized, double-blind, placebo-controlled, single center study evaluating single and multiple ascending intravenous doses of FR104 in healthy subjects.

Condition: Healthy Volunteers
Sponsor: OSE Immunotherapeutics
Phase 1 

Relates to J Immunol. 2016 Dec 15;197(12):4593-4602. Epub 2016 Nov 14.

Monday
Apr182016

NCT02745756

A Combined Cell Therapy Approach to the Treatment of Neuroblastoma

A Combined Cell Therapy Approach to the Treatment of Neuroblastoma

Conditions: Neuroblastoma, Nerve Tissue Neoplasms
Sponsor: H. Lee Moffitt Cancer Center & Research Institute
Collaborator: All Childrens Hosp Johns HopkinsMedicine 
Phase 1 

Wednesday
Apr132016

NCT02754362

A Toll-like Receptor Agonist as an Adjuvant to Tumor Associated Antigens (TAA) Mixed With Montanide ISA-51 VG With Bevacizumab for Patients With Recurrent Glioblastoma

Determine the immunogenicity and efficacy of a vaccine composed of tumor associated long synthetic peptides mixed with Montanide ISA-51 VG administered with polyinosinic-polycytidylic acid-poly-L-lysine carboxymethylcellulose (Poly-ICLC) and bevacizumab in adults with recurrent glioblastoma.

Conditions: Glioblastoma, Glioma
Sponsor: New York University School of Medicine
Collaborator:  Mount Sinai Hospital, New York
Phase 2 

Thursday
Mar312016

NCT00558051

Alpha-type-1 Dendritic Cell-based Vaccines in Patients With Metastatic Colorectal Cancer

Phase I Evaluation of Semi-continuous Alpha-type-1 Dendritic Cell-based Vaccines in Patients With Metastatic Colorectal Cancer

Condition: Metastatic Colorectal Cancer
Sponsor: Pawel Kalisnki, Universiy of Pittsburgh

Phase 1

Relates to JIC Article April 2016

Tuesday
Nov172015

NCT02665364

Study of IFN-K in Systemic Lupus Erythematosus

A Phase IIb, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Neutralization of the Interferon Gene Signature and the Clinical Efficacy of IFNα-Kinoid in Adult Subjects With Systemic Lupus Erythematosus

Condition: Systemic Lupus Erythematosus
Sponsor: Neovacs
Phase 2 

Friday
Oct092015

NCT02579252

24 Months Safety and Efficacy Study of AADvac1 in Patients with Mild Alzheimer's Disease (ADAMANT)

A 24 Months Randomised, Placebo-controlled, Parallel Group, Double Blinded, Multi Centre, Phase 2 Study to Assess Safety and Efficacy of AADvac1 Applied to Patients With Mild Alzheimer's Disease

Condition: Alzheimer's Disease
Sponsor: Axon Neuroscience SE
Phase 2 

Monday
Oct052015

NCT02576145

A Study to Assess Immune Response in Pediatric Kidney Transplant Recipients Treated With Daclizumab (Zenapax)

Immune Response to Neoantigen and Recall Antigen in Pediatric Renal Transplant Recipients Treated With the IL-2R Alfa Monoclonal Antibody, Daclizumab (Zenapax®)

Sponsor: Hoffman-La Roche
Condition: Kidney Transplantation
Phase 4