KLH in Clinical Trials

Clinical trials involving KLH. Details such as study status, design and investigators are available by link to outside sites.

Clinical trial links are intended for informational purposes only, and are not solicitations for any study nor provided for the purposes of giving medical advice. See Terms of Use for this site.

(in order by date)

Entries in Diagnostic Antigen (36)

Monday
Jan302017

2017-000084-32

Friday
May202016

NCT02800811

Safety, Tolerability, PK, PD, and Immunogenicity of Single and Multiple Ascending Intravenous Doses of FR104

First-in-human, phase I, randomized, double-blind, placebo-controlled, single center study evaluating single and multiple ascending intravenous doses of FR104 in healthy subjects.

Condition: Healthy Volunteers
Sponsor: OSE Immunotherapeutics
Phase 1 

Relates to J Immunol. 2016 Dec 15;197(12):4593-4602. Epub 2016 Nov 14.

Wednesday
Apr132016

NCT02754362

A Toll-like Receptor Agonist as an Adjuvant to Tumor Associated Antigens (TAA) Mixed With Montanide ISA-51 VG With Bevacizumab for Patients With Recurrent Glioblastoma

Determine the immunogenicity and efficacy of a vaccine composed of tumor associated long synthetic peptides mixed with Montanide ISA-51 VG administered with polyinosinic-polycytidylic acid-poly-L-lysine carboxymethylcellulose (Poly-ICLC) and bevacizumab in adults with recurrent glioblastoma.

Conditions: Glioblastoma, Glioma
Sponsor: New York University School of Medicine
Collaborator:  Mount Sinai Hospital, New York
Phase 2 

Monday
Oct052015

NCT02576145

A Study to Assess Immune Response in Pediatric Kidney Transplant Recipients Treated With Daclizumab (Zenapax)

Immune Response to Neoantigen and Recall Antigen in Pediatric Renal Transplant Recipients Treated With the IL-2R Alfa Monoclonal Antibody, Daclizumab (Zenapax®)

Sponsor: Hoffman-La Roche
Condition: Kidney Transplantation
Phase 4 

 

Tuesday
Sep082015

NCT02545868

This multicenter, randomized, open-label study will evaluate the immune response to vaccines (tetanus toxoid [TT], 23-valent pneumococcal polysaccharide vaccine [23-PPV], influenza vaccine, and keyhole limpet hemocyanin [KLH]) after administration of a dose of ocrelizumab (OCR) in participants with relapsing multiple sclerosis (RMS).
Condition: Multiple Sclerosis, Relapsing-Remitting
Sponsor: Hoffman-LaRoche
Phase 3 
Tuesday
Jan062015

NCT02334735

A Comparison of Matured Dendritic Cells and Montanide® in Study Subjects With High Risk of Melanoma Recurrence

A Phase II Open Label, Randomized Study of Poly-ICLC Matured DC as an Adjuvant for NY-ESO-1 and Melan-A/MART-1 Peptide Vaccination Compared to Montanide® ISA-51 VG, in Study Subjects With Melanoma in Complete Clinical Remission But at High Risk of Disease Recurrence

Conditions: Melanoma
Sponsor: Nina Bhardwaj
Collaborators: New York University School of Medicine, Memorial Sloan-Kettering Cancer Center, Ludwig Institute for Cancer Research, Melanoma Research Alliance, Oncovir Inc.
Phase 2

Tuesday
Mar252014

NCT02097849

A Phase 3b Study of BG00012's Effect on Vaccination Response in Subjects With Relapsed Forms of Multiple Sclerosis

A Randomized, Open-Label Study to Assess the Effects of BG00012 on the Immune Response to Vaccination and on Lymphocyte Subsets in Subjects With Relapsing Forms of Multiple Sclerosis

Conditions: Mulitple Sclerosis
Sponsor: Biogen Idec
Phase  III

Tuesday
Mar042014

NCT02079480

Study to Evaluate the Safety, Tolerability, PK, and PD of CD40 in Healthy Subjects (CD40 FIH)

Condition: n/a  (Healthy Adults)
Sponsor: Bristol-Myers Squibb
Phase I

Thursday
Feb142013

NCT01910662

Tuesday
Jul172012

NCT01644968

Phase 1 Study of Anti-OX40 in Patients With Advanced Cancer

Conditions: Advanced Cancer
Sponsors: Providence Health & Services
Phase: I 

Relates to article in Cancer Research