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KLH in Publications

Publications of scientific research involving KLH. Abstracts or full text articles are available by link to outside sites. If you know of a KLH-related publication that is not yet on KLH Site™, let us know.

(in order by date)

Thursday
Dec152016

First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28

Poirier NBlancho GHiance MMary CVan Assche TLempoels JRamael SWang WThepenier VBraudeau CSalabert NJosien RAnderson IGourley ISoulillou JPCoquoz DVanhove B

J Immunol. 2016 Dec 15;197(12):4593-4602. Epub 2016 Nov 14.

Relates to Clinical Trial NCT02800811

Monday
Oct312016

Clinical study of a survivin long peptide vaccine (SurVaxM) in patients with recurrent malignant glioma.

Fenstermaker RACiesielski MJQiu JYang NFrank CLLee KPMechtler LRBelal AAhluwalia MSHutson AD

Cancer Immunol Immunother. 2016 Nov;65(11):1339-1352. Epub 2016

Friday
Jun242016

Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients

Steve Boudewijns, Harm Westdorp, Rutger H.T. Koornstra, Erik H.J.G. Aarntzen, Gerty Schreibelt, Jeroen H.A. Creemers, Cornelis J.A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Winald R. Gerritsen, and Kalijn F. Bol

 

 

 

Wednesday
Jun012016

FRI0230 Assessment of Safety, Pharmacokinetics and Pharmacodynamics of A Novel anti-CD40 Monoclonal antibody, CFZ533, in Healthy Volunteers and in Rheumatoid Arthritis Patients

A. SladeP. Koo, Y. He, P. Espie, A. Auger-Sarrazin, J. Rush, P. Gergely

Annals of the Rheumatic Diseases, June 2016; Vol 75, Issue Suppl 2.

Wednesday
May112016

Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.

BelsonSchmidtFernandoHardesScottBrettClark, OliveiraDavisMcHughStone.

Inflamm Res. 2016 May;65(5):389-404. doi: 10.1007/s00011-016-0923-4. Epub 2016 Mar 11.

Friday
Apr222016

A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission

Roisin E. O’Cearbhaill, Govind Ragupathi, Jianglong Zhu, Qian Wan, Svetlana Mironov, Guangbin Yang, Maria K. Spassova, Alexia Iasonos, Sara Kravetz, Ouathek Ouerfelli, David R. Spriggs, Samuel J. Danishefsky and Paul J. Sabbatini.

Cancers 20168(4), 46; doi:10.3390/cancers8040046

Tuesday
Apr192016

Prolonged intralymphatic delivery of dendritic cells through implantable lymphatic ports in patients with advanced cancer

Michal Radomski, Herbert J. Zeh, Howard D. Edington, James F. Pingpank, Lisa H. Butterfield,Theresa L. Whiteside, Eva Wieckowski, David L. Bartlett, Pawel Kalinski

DOI: 10.1186/s40425-016-0128-y

Friday
Apr082016

Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus

B A Sullivan, W Tsuji, A Kivitz, J Peng, G E Arnold, M J Boedigheimer, K Chiu, C L Green, A Kaliyaperumal, C Wang, J Ferbas, and J B Chung

Lupus Sci Med. 2016; 3(1): e000146.
Published online 2016 Apr 8. doi:  10.1136/lupus-2016-000146

Relates to Clinical Trials: NCT02391259 and NCT00774943

 

Friday
Apr012016

Trophic Relationships between Two Gastropods and Seaweeds in Subtropical Rocky Reefs Based on Stable Isotope Analyses

Alejandra Piñón-Gimate, Mercedes M. Gómez-Valdez, Alejandra Mazariegos-Villarreal and Elisa Serviere-Zaragoza.

Journal of Shellfish Research 35(1):191-197. 2016

Full text 

Tuesday
Mar012016

The Design of a Clostridium diffi cile Carbohydrate-Based Vaccine

Mario A. Monteiro

Chapter 21
Vaccine Design: Methods and Protocols: Volume 1: Vaccines for Human Diseases, Methods in Molecular Biology
 

Sunil Thomas (ed.), Vaccine Design: Methods and Protocols: Volume 1: Vaccines for Human Diseases, Methods in Molecular Biology, vol. 1403, DOI 10.1007/978-1-4939-3387-7_21, © Springer Science+Business Media New York 2016 

 

Monday
Feb082016

Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: Clinical and immunological data of a phase I/II clinical trial

MORENA ANTONILLI, HASSAN RAHIMI, VALERIA VISCONTI, CHIARA NAPOLETANO, ILARY RUSCITOLARIA GRAZIA ZIZZARI, SALVATORE CAPONNETTO, GIACOMO BARCHIESI, ROBERTA IADAROLA, LUCA PIERELLI, AURELIA RUGHETTI, FILIPPO BELLATI, PIERLUIGI BENEDETTI PANICI, and MARIANNA NUTI2 

 

 

Saturday
Feb062016

Clinical Safety and Immunogenicity of Tumor-Targeted, Plant-Made Id-KLH Conjugate Vaccines for Follicular Lymphoma

Daniel Tusé, Nora Ku, Maurizio Bendandi, Carlos Becerra, Robert Collins Jr., Nyla Langford, Susana Inogés Sancho, Ascensión López-Díaz de Cerio, Fernando Pastor, Romy Kandzia, Frank Thieme, Franziska Jarczowski, Dieter Krause, Julian K.-C. Ma, Shan Pandya, Victor Klimyuk, Yuri Gleba, and John E. Butler-Ransohoff.

BioMed Research InternationalVolume 2015 (2015), Article ID 648143 
http://dx.doi.org/10.1155/2015/648143

Thursday
Jan212016

Development of a 20N Virus Filtration Process for Keyhole Limpet Hemocyanin (KLH) – A High Molecular Weight Protein

L. Milbrandt, C. Brisson, Z. Aguilar, W. Bailey.

Poster presented January 21, 2016

PepTalk
Protein Science Week Conference
San Diego, California
Jan 18-22, 2016 

Friday
Jan012016

Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis.

Semerano LDuvallet EBelmellat NMarival NSchall NMonteil MGrouard-Vogel GBernier ELecouvey MHlawaty HMuller SBoissier MCAssier E.

Angiogenesis. 2016 Jan;19(1):39-52. doi: 10.1007/s10456-015-9487-0. Epub 2015 Sep 29.

Saturday
Dec052015

Dendritic cell vaccines containing lymphocytes produce improved immunogenicity in patients with cancer

Mayu O Frank, Julia Kaufman, Salina Parveen, Nathalie E Blachère, Dana E Orange, and Robert B Darnell

J Transl Med. 2014; 12: 338.
Published online 2014 Dec 5. doi:  10.1186/s12967-014-0338-3

 

Relates to Clinical Trials:
NCT00289341NCT00345293, and NCT00893945

 

Friday
Dec042015

Clostridium difficile Surface Polysaccharide-KLH Conjugate Vaccine Induced Th17-Featured Adaptive Immune Responses in Mice

Shuguang Bi

Poster presented December 4, 2015

Society for Glycobiology 2015 Annual Meeting
San Francisco, California
December 1-4, 2015 

Tuesday
Dec012015

The giant keyhole limpet radular teeth: A naturally-grown harvest machine

Tina Ukmar-Godec, Gregor KapunPaul ZaslanskyDamien Faivre

J Structural Biology, Vol 192, 3, Dec 2015; 392-402.

 

Tuesday
Dec012015

Radula Development in the Giant Key-Hole Limpet Megathura crenulata

Adrienne Mikovari, Jonathan Williams, Frank Oakes, Robert Brandon Lincicum, Amanda J. Zellmer and Gary G. Martin

Journal of Shellfish Research Dec 2015 : Vol. 34, Issue 3, pg(s) 893-902 doi: 10.2983/035.034.0319

Tuesday
Dec012015

Behavioral thermoregulation and critical thermal limits of giant keyhole limpet Megathura crenulata(Sowerby 1825) (Mollusca; Vetigastropoda)

Díaz FDenisse Re ASalas AGalindo-Sanchez CEGonzalez MASanchez A, Rosas C

J Therm Biol. 2015 Dec;54:133-8. doi: 10.1016/j.jtherbio.2013.05.007. Epub 2013 Jun 6.

Friday
Sep252015

CFZ533: Assessment of Immunomodulatory Activity Following Single Doses of a Novel Anti-CD40 mAb in Healthy Volunteers

A. Slade, J. Doucet, P. Koo, P. Espie, J. Rush, C. Tomek, J. Klupp. (Novarits and Celerion)

Abstract #2007 from the 2015 American Transplant Congress
American Society of Transplantation
Grapevine, Texas
Sep 25-27, 2015