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KLH in Publications

Publications of scientific research involving KLH. Abstracts or full text articles are available by link to outside sites. If you know of a KLH-related publication that is not yet on KLH Site™, let us know.

(in order by date)


Clinical study of a survivin long peptide vaccine (SurVaxM) in patients with recurrent malignant glioma.

Fenstermaker RACiesielski MJQiu JYang NFrank CLLee KPMechtler LRBelal AAhluwalia MSHutson AD

Cancer Immunol Immunother. 2016 Nov;65(11):1339-1352. Epub 2016


Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.

BelsonSchmidtFernandoHardesScottBrettClark, OliveiraDavisMcHughStone.

Inflamm Res. 2016 May;65(5):389-404. doi: 10.1007/s00011-016-0923-4. Epub 2016 Mar 11.


A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission

Roisin E. O’Cearbhaill, Govind Ragupathi, Jianglong Zhu, Qian Wan, Svetlana Mironov, Guangbin Yang, Maria K. Spassova, Alexia Iasonos, Sara Kravetz, Ouathek Ouerfelli, David R. Spriggs, Samuel J. Danishefsky and Paul J. Sabbatini.

Cancers 20168(4), 46; doi:10.3390/cancers8040046


Prolonged intralymphatic delivery of dendritic cells through implantable lymphatic ports in patients with advanced cancer

Michal Radomski, Herbert J. Zeh, Howard D. Edington, James F. Pingpank, Lisa H. Butterfield,Theresa L. Whiteside, Eva Wieckowski, David L. Bartlett, Pawel Kalinski

DOI: 10.1186/s40425-016-0128-y


Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus

B A Sullivan, W Tsuji, A Kivitz, J Peng, G E Arnold, M J Boedigheimer, K Chiu, C L Green, A Kaliyaperumal, C Wang, J Ferbas, and J B Chung

Lupus Sci Med. 2016; 3(1): e000146.
Published online 2016 Apr 8. doi:  10.1136/lupus-2016-000146

Relates to Clinical Trials: NCT02391259 and NCT00774943



Trophic Relationships between Two Gastropods and Seaweeds in Subtropical Rocky Reefs Based on Stable Isotope Analyses

Alejandra Piñón-Gimate, Mercedes M. Gómez-Valdez, Alejandra Mazariegos-Villarreal and Elisa Serviere-Zaragoza.

Journal of Shellfish Research 35(1):191-197. 2016

Full text 


The Design of a Clostridium diffi cile Carbohydrate-Based Vaccine

Mario A. Monteiro

Chapter 21
Vaccine Design: Methods and Protocols: Volume 1: Vaccines for Human Diseases, Methods in Molecular Biology

Sunil Thomas (ed.), Vaccine Design: Methods and Protocols: Volume 1: Vaccines for Human Diseases, Methods in Molecular Biology, vol. 1403, DOI 10.1007/978-1-4939-3387-7_21, © Springer Science+Business Media New York 2016 



Clinical Safety and Immunogenicity of Tumor-Targeted, Plant-Made Id-KLH Conjugate Vaccines for Follicular Lymphoma

Daniel Tusé, Nora Ku, Maurizio Bendandi, Carlos Becerra, Robert Collins Jr., Nyla Langford, Susana Inogés Sancho, Ascensión López-Díaz de Cerio, Fernando Pastor, Romy Kandzia, Frank Thieme, Franziska Jarczowski, Dieter Krause, Julian K.-C. Ma, Shan Pandya, Victor Klimyuk, Yuri Gleba, and John E. Butler-Ransohoff.

BioMed Research InternationalVolume 2015 (2015), Article ID 648143


Development of a 20N Virus Filtration Process for Keyhole Limpet Hemocyanin (KLH) – A High Molecular Weight Protein

L. Milbrandt, C. Brisson, Z. Aguilar, W. Bailey.

Poster presented January 21, 2016

Protein Science Week Conference
San Diego, California
Jan 18-22, 2016 


Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis.

Semerano LDuvallet EBelmellat NMarival NSchall NMonteil MGrouard-Vogel GBernier ELecouvey MHlawaty HMuller SBoissier MCAssier E.

Angiogenesis. 2016 Jan;19(1):39-52. doi: 10.1007/s10456-015-9487-0. Epub 2015 Sep 29.


Clostridium difficile Surface Polysaccharide-KLH Conjugate Vaccine Induced Th17-Featured Adaptive Immune Responses in Mice

Shuguang Bi

Poster presented December 4, 2015

Society for Glycobiology 2015 Annual Meeting
San Francisco, California
December 1-4, 2015 


The giant keyhole limpet radular teeth: A naturally-grown harvest machine

Tina Ukmar-Godec, Gregor KapunPaul ZaslanskyDamien Faivre

J Structural Biology, Vol 192, 3, Dec 2015; 392-402.



Radula Development in the Giant Key-Hole Limpet Megathura crenulata

Adrienne Mikovari, Jonathan Williams, Frank Oakes, Robert Brandon Lincicum, Amanda J. Zellmer and Gary G. Martin

Journal of Shellfish Research Dec 2015 : Vol. 34, Issue 3, pg(s) 893-902 doi: 10.2983/035.034.0319


Behavioral thermoregulation and critical thermal limits of giant keyhole limpet Megathura crenulata(Sowerby 1825) (Mollusca; Vetigastropoda)

Díaz FDenisse Re ASalas AGalindo-Sanchez CEGonzalez MASanchez A, Rosas C

J Therm Biol. 2015 Dec;54:133-8. doi: 10.1016/j.jtherbio.2013.05.007. Epub 2013 Jun 6.


CFZ533: Assessment of Immunomodulatory Activity Following Single Doses of a Novel Anti-CD40 mAb in Healthy Volunteers

A. Slade, J. Doucet, P. Koo, P. Espie, J. Rush, C. Tomek, J. Klupp. (Novarits and Celerion)

Abstract #2007 from the 2015 American Transplant Congress
American Society of Transplantation
Grapevine, Texas
Sep 25-27, 2015 


IFNα kinoid induces neutralizing anti-IFNα antibodies that decrease the expression of IFN-induced and B cell activation associated transcripts : analysis of extended follow-up data from the IFN-K phase I/II study

J. Ducreux1, P. Vandepapeliere2, F. Colaone2, C. Roucairol2, T. Croughs2, F. A. Houssiau1, G. Grouard-Vogel2, B. Lauwerys1
(1Université catholique de Louvain, Brussels, Belgium, 2Neovacs, Paris, France)

Poster presented September 4, 2015

Lupus 2015
11th International Congress on Systemic Lupus Erythematosus
Vienna, Austria
Sept. 2 - 6, 2015


Lymphoma Immunotherapy: Current Status

Roberta Zappasodi, Filippo de Braud, and Massimo Di Nicola.

Front Immunol. 2015; 6: 448
Published online 2015 Sep 1. doi: 10.3389/fimmu.2015.00448 


Effects of active anti-methamphetamine vaccination on intravenous self-administration in rats.

Miller MLAarde SMMoreno AYCreehan KMJanda KDTaffe MA.

Drug Alcohol Depend. 2015 Jun 19. [Epub ahead of print]


Long-lasting humoral immune response induced in HIV-1-infected patients by a synthetic peptide (AT20) derived from the HIV-1 matrix protein p17 functional epitope

Emanuele FocàMaria Luisa IariaFrancesca CaccuriSimona FiorentiniDavide MottaCinzia GiagulliFrancesco CastelliArnaldo Caruso

HIV Clin Trials. 2015 Jun 9:1528433614Z0000000018. [Epub ahead of print]


Measuring Properties of Different Forms of Keyhole Limpet Hemocyanin (KLH) Reveals Important Differences

Shuguang Bi, Ph.D., Laura Milbrandt, Catherine Brisson, Ph.D.

Poster presented May 8-12, 2015

Immunology 2015
Annual Meeting of American Association of Immunologists
New Orleans, LA
May 8-12, 2015