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KLH in Publications

Publications of scientific research involving KLH. Abstracts or full text articles are available by link to outside sites. If you know of a KLH-related publication that is not yet on KLH Site™, let us know.

(in order by date)

Entries in Rheumatoid Arthritis (11)

Wednesday
Jun012016

FRI0230 Assessment of Safety, Pharmacokinetics and Pharmacodynamics of A Novel anti-CD40 Monoclonal antibody, CFZ533, in Healthy Volunteers and in Rheumatoid Arthritis Patients

A. SladeP. Koo, Y. He, P. Espie, A. Auger-Sarrazin, J. Rush, P. Gergely

Annals of the Rheumatic Diseases, June 2016; Vol 75, Issue Suppl 2.

Friday
Jan012016

Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis.

Semerano LDuvallet EBelmellat NMarival NSchall NMonteil MGrouard-Vogel GBernier ELecouvey MHlawaty HMuller SBoissier MCAssier E.

Angiogenesis. 2016 Jan;19(1):39-52. doi: 10.1007/s10456-015-9487-0. Epub 2015 Sep 29.

Thursday
Sep132012

Discovery and in Vivo Evaluation of Dual PI3Kβ/δ Inhibitors

Gonzalez-Lopez de Turiso F, Shin Y, Brown M, Cardozo M, Chen Y, Fong D, Hao X, He X, Henne K, Hu YL, Johnson MG, Kohn T, Lohman J, McBride HJ, McGee LR, Medina JC, Metz D, Miner K, Mohn D, Pattaropong V, Seganish J, Simard JL, Wannberg S, Whittington DA, Yu G, Cushing TD.

J Med Chem. 2012 Sep 13;55(17):7667-85. Epub 2012 Aug 29

Thursday
Aug092012

Discovery and In Vivo Evaluation of Dual PI3Kβ/δ Inhibitors.

Gonzalez-Lopez de Turiso F, Shin Y, Brown M, Cardozo M, Chen Y, Fong D, Hao X, He X, Henne K, Hu YL, Johnson MG, Kohn T, Lohman J, McBride HJ, McGee LR, Medina JC, Metz DP, Miner K, Mohn D, Pattaropong V, Seganish J, Simmard JL, Wannberg S, Whittington DA, Yu G, Cushing TD

J Med Chem. 2012 Aug 9. [Epub ahead of print]

Friday
Jun082012

Active Therapeutic Immunization with TNF-Kinoid in Rheumatoid Arthritis Patients with Secondary Resistance to TNFα Antagonists is safe and immunogenic.

Durez P, Miranda P , Toncheva A, Berman A, Rillo OL, Boutsen Y, Kehler T, Mociran E, Soto Saez LA, Fautrel B, Mariette X, Solakov P, Lucero E, Vlak T, Grazio S, Mastrovic K, Chiriac R, Grouard-Vogel G, Dhellin O, Ouary S, Vandepapelière P, Boissier MC

Eular 2012 (June 8-9)

Tuesday
May012012

Modulation of anti-tumor necrosis factor alpha (TNF-α) antibody secretion in mice immunized with TNF-α kinoid.

Assier E, Semerano L, Duvallet E, Delavallée L, Bernier E, Laborie M, Grouard-Vogel G, Larcier P, Bessis N, Boissier MC

Clin Vaccine Immunol. 2012 May;19(5):699-703. doi: 10.1128/CVI.05649-11. Epub 2012 Mar 21.

Thursday
Nov172011

Active immunization against IL-23p19 improves experimental arthritis

Ratsimandresy RA, Duvallet E, Assier E, Semerano L, Delavallée L, Bessis N, Zagury JF, Boissier MC.

Vaccine. 2011 Nov 21;29(50):9329-36. Epub 2011 Oct 18

Friday
Apr012011

Kinoid of human tumor necrosis factor-alpha for rheumatoid arthritis.

Monday
Mar012010

VEGF targeting by active immunisation improves joint inflammation and destruction in a murine model of rheumatoid arthritis

E AssierL SemeranoL DelavalleeD DamotteG Grouard-VogelE BernierD ZaguryN Bessis, M C Boissier

Ann Rheum Dis2010;69:A46 doi:10.1136/ard.2010.129635h

Friday
Jan012010

Immunization responses in rheumatoid arthritis patients treated with rituximab: results from a controlled clinical trial

Bingham CO 3rd, Looney RJ, Deodhar A, Halsey N, Greenwald M, Codding C, Trzaskoma B, Martin F, Agarwal S, Kelman A.

Arthritis Rheum 2010 Jan;62(1):64-74

Friday
Oct242008

Results From A Controlled Clinical Trial (SIERRA) To Evaluate Primary And Recall Responses To Immunizations In RA Patients Treated With Rituximab

C. Bingham, Genentech; Wyeth; Johns Hopkins University; Abbott; Amgen; Novartis; Merck; Genentech; Targeted Genetics; Abbott; Amgen; BMS; Centocor; Genentech; R. Looney, Genentech; Amgen; IDEC/Biogen; Roche; Proteolix; A. Deodhar, Genentech; Centocor; Centocor; Genentech; Genentech; Centocor; N. Halsey, Vanguard; Wyeth laboratories; Centers for Disease Control and Prevention; NIH; PATH; Johns Hopkins University; Glaxo Smith Kline; Merck; Wyeth; Genentech; Director, Institute for Vaccine Safety, Johns Hopkins University; M. Greenwald, Genentech; Biogen Idec; C. Codding, Genentech; B. Trzaskoma, Genentech, Inc.; A. Kelman, Genentech, Inc.; Genentech, Inc.
San Francisco, CA
October 24-29, 2008