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KLH in Publications

Publications of scientific research involving KLH. Abstracts or full text articles are available by link to outside sites. If you know of a KLH-related publication that is not yet on KLH Site™, let us know.

(in order by date)

Entries in Model - Rat (51)

Tuesday
Aug202013

T-cell-dependent antibody responses in the rat: Forms and sources of keyhole limpet hemocyanin matter

Lebrec H, Hock MB, Sundsmo JS, Mytych DT, Chow H, Carlock LL, Joubert MK, Reindel J, Zhou L, Bussiere JL.

J Immunotoxicology 2013 August 20 (Epub ahead of print)

 

Tuesday
Mar052013

T Cell Dependent Antibody Responses in the Rat: Forms and Sources of Keyhole Limpet Hemocyanin Matter

H. Lebrec1, M. B. Hock2, J. Sundsmo3, D. Mytych2, H. Chow3, L. Carlock1, M. K. Joubert2 and J. L. Bussiere2. 1 Amgen, Seattle, WA; 2 Amgen, Thousand Oaks, CA; 3 Stellar Biotechnologies, Port Hueneme, CA.

Abstract published March 2013 online.

Poster presented March 14, 2013.

The Toxicologist
Supplement to Toxicological Sciences
An Official Journal of the Society of Toxicology
ISSN 1096-6080
Volume 132, Issue 1, Page 440
March 2013

 

Thursday
Feb142013

Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens

Pravetoni M, Le Naour M, Tucker AM, Harmon TM, Hawley TM, Portoghese PS, Pentel PR

J Med Chem. 2013 Feb 14;56(3):915-23. doi: 10.1021/jm3013745. Epub 2013 Jan 15

Friday
Feb012013

Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats

Raleigh MD, Pravetoni M, Harris AC, Birnbaum AK, Pentel PR

J Pharmacol Exp Ther. 2013 Feb;344(2):397-406. doi: 10.1124/jpet.112.201194. Epub 2012 Dec 7

Friday
Feb012013

Developmental immunotoxicity of ethanol in an extended one-generation reproductive toxicity study.

Tonk EC, de Groot DM, Wolterbeek AP, Penninks AH, Waalkens-Berendsen ID, Piersma AH, van Loveren H

Arch Toxicol. 2013 Feb;87(2):323-35. doi: 10.1007/s00204-012-0940-1. Epub 2012 Sep 25

Tuesday
Jan012013

Evaluation of primary and secondary responses to a T-cell-dependent antigen, keyhole limpet hemocyanin, in rats

Kawai R, Ito S, Aida T, Hattori H, Kimura T, Furukawa T, Mori K, Sanbuissho A, Kawada T

J Immunotoxicol. 2013 Jan;10(1):40-8. doi: 10.3109/1547691X.2012.691122. Epub 2012 Sep 7

Monday
Oct222012

A Methamphetamine Vaccine Attenuates Methamphetamine-Induced Disruptions in Thermoregulation and Activity in Rats

Miller ML, Moreno AY, Aarde SM, Creehan KM, Vandewater SA, Vaillancourt BD, Wright MJ Jr, Janda KD, Taffe MA

Biol Psychiatry. 2012 Oct 22. pii: S0006-3223(12)00803-7. doi: 10.1016/j.biopsych.2012.09.010. [Epub ahead of print]

Tuesday
Sep252012

Developmental immunotoxicity of ethanol in an extended one-generation reproductive toxicity study.

Tonk EC, de Groot DM, Wolterbeek AP, Penninks AH, Waalkens-Berendsen ID, Piersma AH, van Loveren H.

Arch Toxicol. 2012 Sep 25. [Epub ahead of print]

Thursday
Sep132012

Discovery and in Vivo Evaluation of Dual PI3Kβ/δ Inhibitors

Gonzalez-Lopez de Turiso F, Shin Y, Brown M, Cardozo M, Chen Y, Fong D, Hao X, He X, Henne K, Hu YL, Johnson MG, Kohn T, Lohman J, McBride HJ, McGee LR, Medina JC, Metz D, Miner K, Mohn D, Pattaropong V, Seganish J, Simard JL, Wannberg S, Whittington DA, Yu G, Cushing TD.

J Med Chem. 2012 Sep 13;55(17):7667-85. Epub 2012 Aug 29

Saturday
Sep082012

Evaluation of primary and secondary responses to a T-cell-dependent antigen, keyhole limpet hemocyanin, in rats

Kawai R, Ito S, Aida T, Hattori H, Kimura T, Furukawa T, Mori K, Sanbuissho A, Kawada T

J Immunotoxicol. 2012 Sep 7. [Epub ahead of print]

Wednesday
Sep052012

Dietary intake of resveratrol enhances the adaptive immunity of aged rats

Friday
Aug172012

Combined Cocaine Hydrolase Gene Transfer and Anti-Cocaine Vaccine Synergistically Block Cocaine-Induced Locomotion

Carroll ME, Zlebnik NE, Anker JJ, Kosten TR, Orson FM, Shen X, Kinsey B, Parks RJ, Gao Y, Brimijoin S

 

 

Monday
Apr022012

An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia

Pravetoni M, Le Naour M, Harmon TM, Tucker AM, Portoghese PS, Pentel PR.

J Pharmacol Exp Ther. 2012 Apr;341(1):225-32. Epub 2012 Jan 18.

Thursday
Mar012012

Pathological, immunological and biochemical markers of subchronic arsenic toxicity in rats

Wednesday
Feb152012

Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities

Pravetoni M, Keyler DE, Pidaparthi RR, Carroll FI, Runyon SP, Murtaugh MP, Earley CA, Pentel PR.

Biochem Pharmacol. 2012 Feb 15;83(4):543-50. Epub 2011 Nov 15.

Wednesday
Jan182012

An oxycodone conjugate vaccine elicits oxycodone-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia

Pravetoni M, Le Naour M, Harmon T, Tucker A, Portoghese PS, Pentel PR.

J Pharmacol Exp Ther. 2012 Jan 18. Epub.

Thursday
Jul282011

Developmental immunotoxicity of di-n-octyltin dichloride (DOTC) in an extended one-generation reproductive toxicity study

Tonk EC, de Groot DM, Penninks AH, Waalkens-Berendsen ID, Wolterbeek AP, Piersma AH, van Loveren H.

Toxicol Lett. 2011 Jul 28;204(2-3):156-63. Epub 2011 Apr 30.

Friday
Jan012010

Effects of perinatal exposure to the brominated flame-retardant hexabromocyclododecane (HBCD) on the developing immune system in rats

Hachisuka A, Nakamura R, Sato Y, Nakamura R, Shibutani M, Teshima R.

Article in Japanese.
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 2010;(128):58-64

Friday
Jan012010

The T-dependent antibody response to keyhole limpet hemocyanin in rodents

Plitnick LM, Herzyk DJ.

Methods Mol Biol. 2010;598:159-71

Friday
Jun152007

Immunotoxicity assessment for the novel Spleen tyrosine kinase inhibitor R406

Zhu Y, Herlaar E, Masuda ES, Burleson GR, Nelson AJ, Grossbard EB, Clemens GR.

Toxicol Appl Pharmacol. 2007 Jun 15;221(3):268-77. Epub 2007 Mar 31