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KLH in Publications

Publications of scientific research involving KLH. Abstracts or full text articles are available by link to outside sites. If you know of a KLH-related publication that is not yet on KLH Site™, let us know.

(in order by date)

Entries in Dendritic Cell (66)

Friday
Jun242016

Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients

Steve Boudewijns, Harm Westdorp, Rutger H.T. Koornstra, Erik H.J.G. Aarntzen, Gerty Schreibelt, Jeroen H.A. Creemers, Cornelis J.A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Winald R. Gerritsen, and Kalijn F. Bol

 

 

 

Tuesday
Apr192016

Prolonged intralymphatic delivery of dendritic cells through implantable lymphatic ports in patients with advanced cancer

Michal Radomski, Herbert J. Zeh, Howard D. Edington, James F. Pingpank, Lisa H. Butterfield,Theresa L. Whiteside, Eva Wieckowski, David L. Bartlett, Pawel Kalinski

DOI: 10.1186/s40425-016-0128-y

Wednesday
Apr012015

Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients

Kalijn F Bol,1,2 Carl G Figdor,1 Erik HJG Aarntzen,1,3 et al.

Oncoimmunology. 2015 Aug; 4(8): e1019197.
Published online 2015 Apr 1. doi:  10.1080/2162402X.2015.1019197

 

Relates to Clinical Trial NCT01530698.

 

Wednesday
Mar042015

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells

Lei Qiu, Jie Li, Shichong Yu, Qianli Wang, Yinghua Li, Zhenlin Hu, Qiuye Wu, Zhongwu Guo, and Junping Zhang

 

 

Monday
Feb042013

Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells

Aarntzen EH, Srinivas M, Bonetto F, Cruz LJ, Verdijk P, Schreibelt G, van de Rakt MW, Lesterhuis WJ, Van Riel M, Punt CJ, Adema GJ, Heerschap A, Figdor CG, Oyen WJ, de Vries IJ

Clin Cancer Res. 2013 Feb 4. [Epub ahead of print]

Tuesday
Jan012013

Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination

Aarntzen EH, De Vries IJ, Lesterhuis WJ, Schuurhuis D, Jacobs JF, Bol K, Schreibelt G, Mus R, De Wilt JH, Haanen JB, Schadendorf D, Croockewit A, Blokx WA, Van Rossum MM, Kwok WW, Adema GJ, Punt CJ, Figdor CG.

Cancer Res. 2013 Jan 1;73(1):19-29. doi: 10.1158/0008-5472.CAN-12-1127. Epub 2012 Oct 18.

Sunday
Oct282012

Dendritic cell-based vaccination in metastatic melanoma patients: Phase II clinical trial

Oshita C, Takikawa M, Kume A, Miyata H, Ashizawa T, Iizuka A, Kiyohara Y, Yoshikawa S, Tanosaki R, Yamazaki N, Yamamoto A, Takesako K, Yamaguchi K, Akiyama Y

Oncol Rep. 2012 Oct;28(4):1131-8. doi: 10.3892/or.2012.1956. Epub 2012 Aug 7.

Thursday
Oct182012

Targeting CD4+ T helper cells improves the induction of anti-tumor responses in dendritic cell based vaccination.

Aarntzen EH, de Vries IJ, Lesterhuis WJ, Schuurhuis D, Jacobs JF, Bol K, Schreibelt G, Mus R, De Wilt JH, Haanen JB, Schadendorf D, Croockewit S, Blokx WA,van Rossum MM, Kwok WW, Adema GJ, Punt CJ, Figdor CG

Cancer Res. 2012 Oct 18. [Epub ahead of print]

 

Relates to Clinical Trial NCT00243594

Monday
Oct012012

Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients

Aarntzen EH, Schreibelt G, Bol K, Lesterhuis WJ, Croockewit AJ, de Wilt JH, van Rossum MM, Blokx WA, Jacobs JF, Duiveman-de Boer T, Schuurhuis DH, Mus R, Thielemans K, de Vries IJ, Figdor CG, Punt CJ, Adema GJ

Clin Cancer Res. 2012 Oct 1;18(19):5460-5470. Epub 2012 Aug 15

Saturday
Apr212012

Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters

Aarntzen EH, de Vries IJ, Göertz JH, Beldhuis-Valkis M, Brouwers HM, van de Rakt MW, van der Molen RG, Punt CJ, Adema GJ, Tacken PJ, Joosten I, Jacobs JF.

Cancer Immunol Immunother. 2012 Apr 21. [Epub ahead of print]

Thursday
Oct202011

Combination therapy of renal cell carcinoma or breast cancer patients with dendritic cell vaccine and IL-2: results from a phase І /II trial

Soyoung Baek, Choung-Soo Kim, Sung-Bae Kim, Yong-man Kim, Seog-Woon Kwon, YongMan Kim, HyunSoo Kim, Hyunah Lee

J Transl Med. 2011 Oct 20;9(1):178

Wednesday
Oct052011

A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients.

Lesterhuis WJ, de Vries IJ, Aarntzen EA, de Boer A, Scharenborg NM, van de Rakt M, van Spronsen DJ, Preijers FW, Figdor CG, Adema GJ, Punt CJ

Br J Cancer. 2010 Oct 26;103(9):1415-21. Epub 2010 Oct 5

Tuesday
Jul192011

Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients.

Lesterhuis WJ, de Vries IJ, Schreibelt G, Lambeck AJ, Aarntzen EH, Jacobs JF, Scharenborg NM, van de Rakt MW, de Boer AJ, Croockewit S, van Rossum MM, Mus R, Oyen WJ, Boerman OC, Lucas S, Adema GJ, Punt CJ, Figdor CG

Clin Cancer Res. 2011 Sep 1;17(17):5725-35. Epub 2011 Jul 19

Saturday
Jan012011

Induction of cellular immune responses in patients with stage-I multiple myeloma after vaccination with autologous idiotype-pulsed dendritic cells.

Röllig C, Schmidt C, Bornhäuser M, Ehninger G, Schmitz M, Auffermann-Gretzinger S

J Immunother. 2011 Jan;34(1):100-6

Friday
Dec312010

Preventing immune rejection through gene silencing

Zhang X, Li M, Min WP
Monday
Nov152010

A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival

Barth RJ Jr, Fisher DA, Wallace PK, Channon JY, Noelle RJ, Gui J, Ernstoff MS

Clin Cancer Res. 2010 Nov 15;16(22):5548-56. Epub 2010 Sep 30

Thursday
Nov112010

Wild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide used

Lesterhuis WJ, Schreibelt G, Scharenborg NM, Brouwer HM, Gerritsen MJ, Croockewit S, Coulie PG, Torensma R, Adema GJ, Figdor CG, de Vries IJ, Punt CJ

Cancer Immunol Immunother. 2011 Feb;60(2):249-60. Epub 2010 Nov 11

Friday
Oct152010

Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients 

Joannes F.M. Jacobs, Cornelis J.A. Punt1, W. Joost Lesterhuis, Roger P.M. Sutmuller, H. Mary-lène H. Brouwer, Nicole M. Scharenborg, Ina S. Klasen, Luuk B. Hilbrands, Carl G. Figdor, I. Jolanda M. de Vries, Gosse J. Adema

Clin Cancer Res October 15, 2010 16; 5067

Wednesday
Sep012010

Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients

Yi Q, Szmania S, Freeman J, Qian J, Rosen NA, Viswamitra S, Cottler-Fox M, Barlogie B, Tricot G, van Rhee F

Br J Haematol. 2010 Sep;150(5):554-64. Epub 2010 Jul 7

Thursday
Feb182010

Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma

Joost P. Hegmans, Joris D. Veltman, Margaretha E. Lambers, I. Jolanda M. de Vries, Carl G. Figdor, Rudi W. Hendriks, Henk C. Hoogsteden, Bart N. Lambrecht and Joachim G. Aerts.

Am J Respir Crit Care Med. 2010 Jun 15;181(12):1383-90. Epub 2010 Feb 18