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KLH in Publications

Publications of scientific research involving KLH. Abstracts or full text articles are available by link to outside sites. If you know of a KLH-related publication that is not yet on KLH Site™, let us know.

(in order by date)

Entries in Addiction (18)

Friday
Jun192015

Effects of active anti-methamphetamine vaccination on intravenous self-administration in rats.

Miller MLAarde SMMoreno AYCreehan KMJanda KDTaffe MA.

Drug Alcohol Depend. 2015 Jun 19. [Epub ahead of print]

Tuesday
Jul152014

Effects of an Oxycodone Conjugate Vaccine on Oxycodone Self-Administration and Oxycodone-Induced Brain Gene Expression in Rats

Marco Pravetoni, Paul R. Pentel, David N. Potter, Elena H. Chartoff, Laura Tally, and Mark G. LeSage

PLOS One. 2014; 9(7): e101807.

Published online Jul 15, 2014. doi: 10.1371/journal.pone.0101807

 

 

Tuesday
Jul012014

Vaccines against drugs of abuse: where are we now?

Monday
May052014

Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats

Pravetoni M, Vervacke JSDistefano MDTucker AMLaudenbach MPentel PR.

PLOS One. 2014 May 5;9(5):e96547

doi: 10.1371/journal.pone.0096547. eCollection 2014.

Tuesday
Feb112014

Modulating Cocaine Vaccine Potency through Hapten Fluorination

Xiaoqing CaiKyoji Tsuchikama, and Kim D. Janda.

J. Am. Chem. Soc., 2013135 (8), pp 2971–2974

Thursday
Aug012013

A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats.

Kosten TAShen XYO'Malley PWKinsey BMLykissa EDOrson FMKosten TR

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45:223-9.

Monday
Feb252013

Enhancing nicotine vaccine immunogenicity with liposomes

Jonathan W. Lockner, Sam On Ho, Karen C. McCague, Su Ming Chiang, Thai Q. Do, Gary Fujii, and Kim D. Janda

Bioorg Med Chem Lett. 2013 Feb 15; 23(4): 975–978. Published online 2012 Dec 27. 

 

Thursday
Feb142013

Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens

Pravetoni M, Le Naour M, Tucker AM, Harmon TM, Hawley TM, Portoghese PS, Pentel PR

J Med Chem. 2013 Feb 14;56(3):915-23. doi: 10.1021/jm3013745. Epub 2013 Jan 15

Friday
Feb012013

Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats

Raleigh MD, Pravetoni M, Harris AC, Birnbaum AK, Pentel PR

J Pharmacol Exp Ther. 2013 Feb;344(2):397-406. doi: 10.1124/jpet.112.201194. Epub 2012 Dec 7

Monday
Oct222012

A Methamphetamine Vaccine Attenuates Methamphetamine-Induced Disruptions in Thermoregulation and Activity in Rats

Miller ML, Moreno AY, Aarde SM, Creehan KM, Vandewater SA, Vaillancourt BD, Wright MJ Jr, Janda KD, Taffe MA

Biol Psychiatry. 2012 Oct 22. pii: S0006-3223(12)00803-7. doi: 10.1016/j.biopsych.2012.09.010. [Epub ahead of print]

Thursday
Sep272012

A vaccine against methamphetamine attenuates its behavioral effects in mice

Friday
Sep072012

Probing the protective effects of a conformationally constrained nicotine vaccine.

Friday
Aug172012

Combined Cocaine Hydrolase Gene Transfer and Anti-Cocaine Vaccine Synergistically Block Cocaine-Induced Locomotion

Carroll ME, Zlebnik NE, Anker JJ, Kosten TR, Orson FM, Shen X, Kinsey B, Parks RJ, Gao Y, Brimijoin S

 

 

Monday
Apr022012

An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia

Pravetoni M, Le Naour M, Harmon TM, Tucker AM, Portoghese PS, Pentel PR.

J Pharmacol Exp Ther. 2012 Apr;341(1):225-32. Epub 2012 Jan 18.

Wednesday
Feb152012

Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities

Pravetoni M, Keyler DE, Pidaparthi RR, Carroll FI, Runyon SP, Murtaugh MP, Earley CA, Pentel PR.

Biochem Pharmacol. 2012 Feb 15;83(4):543-50. Epub 2011 Nov 15.

Wednesday
Jan182012

An oxycodone conjugate vaccine elicits oxycodone-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia

Pravetoni M, Le Naour M, Harmon T, Tucker A, Portoghese PS, Pentel PR.

J Pharmacol Exp Ther. 2012 Jan 18. Epub.

Tuesday
May232000

Cocaine vaccines: Antibody protection against relapse in a rat model

M. Rocío A. Carrera, Jon A. Ashley, Bin Zhou, Peter Wirsching, George F. Koob, and Kim D. Janda

PNAS vol. 97 no. 11 May 23, 2000 

Friday
Mar141997

Immunologic effects of cocaine in prenatally exposed rats and mice

Bohn AA, Forsyth CS, Kerkvliet NI, Frank AA.

Toxicol Lett. 1997 Mar 14;91(1):47-55