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KLH in Publications

Publications of scientific research involving KLH. Abstracts or full text articles are available by link to outside sites. If you know of a KLH-related publication that is not yet on KLH Site™, let us know.

(in order by date)


A novel assay to measure B cell responses to keyhole limpet haemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus

John Ferbas, Shelley S Belouski, Michelle Horner, Arunan Kaliyaperumal, Li Chen, Malcolm Boyce, C Bernie Colaço, Neil McHugh, Vanessa Quick, Richard J Nicholl, Gerald Siu, and James Chung

Br J Clin Pharmacol. 2013 Aug; 76(2): 188–202


Diet of the Keyhole Limpet Megathura crenulata (Mollusca: Gastropoda) in Subtropical Rocky Reefs

Alejandra Mazariegos-Villarreal, Alejandra Piñón-Gimate, Fátima Aguilar-Mora, Marco Medina, and Elisa Serviere-Zaragoza

Journal of Shellfish Research Aug 2013 : Vol. 32, Issue 2, pg(s) 297-303 doi: 10.2983/035.032.0208


A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats.

Kosten TAShen XYO'Malley PWKinsey BMLykissa EDOrson FMKosten TR

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45:223-9.


Antibody, T-cell and dendritic cell immunotherapy for malignant brain tumors

Vidyalakshmi Chandramohan, Duane A Mitchell, Laura A Johnson, John H Sampson, and Darell D Bigner.

Future Oncol. 2013 July; 9(7): 977-990.



Megathura crenulata Post Larval Culture - Bottleneck for a Valuable Medical Resource

Principal Investigator: F. Oakes
Presented by: B. Lincicum
Stellar Biotechnologies, Inc.

Poster presented May 13, 2013

2013 Annual National Science Foundation (NSF) Conference
May 13-16, 2013
Baltimore, MD

Innovative systems and processes that protect generations of the Giant Keyhole Limpet in land-based aquaculture for the purpose of sustainable, environmentally sound KLH protein manufacture.


Density, Distribution, and Size Frequency of Three Emergent Fishery Species in Palos Verdes, CA

Adrienne Mikovari

Poster presented 2013

Occidental College


Carbohydrate-based Clostridium difficile vaccines

Mario A Monteiro, Zuchao Ma, Lisa Bertolo, Yuening Jiao, Luis Arroyo, Douglas Hodgins, Michael Mallozzi, Gayatri Vedantam, Martin Sagermann, John Sundsmo and Herbert Chow

Expert Review of Vaccines April 2013, Vol. 12, No. 4, Pages 421-431 , DOI 10.1586/erv.13.9


T Cell Dependent Antibody Responses in the Rat: Forms and Sources of Keyhole Limpet Hemocyanin Matter

H. Lebrec1, M. B. Hock2, J. Sundsmo3, D. Mytych2, H. Chow3, L. Carlock1, M. K. Joubert2 and J. L. Bussiere2. 1 Amgen, Seattle, WA; 2 Amgen, Thousand Oaks, CA; 3 Stellar Biotechnologies, Port Hueneme, CA.

Abstract published March 2013 online.

Poster presented March 14, 2013.

The Toxicologist
Supplement to Toxicological Sciences
An Official Journal of the Society of Toxicology
ISSN 1096-6080
Volume 132, Issue 1, Page 440
March 2013



Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A

de Medina P, Paillasse MR, Segala G, Al Saati T, Boyes J, Delsol G, Allal C, Marsili S, Silvente-Poirot S, Poirot M.

Biochimie. 2013 Mar;95(3):482-8. doi: 10.1016/j.biochi.2012.06.001. Epub 2012 Jun 16


Enhancing nicotine vaccine immunogenicity with liposomes

Jonathan W. Lockner, Sam On Ho, Karen C. McCague, Su Ming Chiang, Thai Q. Do, Gary Fujii, and Kim D. Janda

Bioorg Med Chem Lett. 2013 Feb 15; 23(4): 975–978. Published online 2012 Dec 27. 



Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens

Pravetoni M, Le Naour M, Tucker AM, Harmon TM, Hawley TM, Portoghese PS, Pentel PR

J Med Chem. 2013 Feb 14;56(3):915-23. doi: 10.1021/jm3013745. Epub 2013 Jan 15


Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer

Yen-Lin Huang, Jung-Tung Hung, Sarah K. C. Cheung, Hsin-Yu Lee, Kuo-Ching Chu, Shiou-Ting Li, Yu-Chen Lin, Chien-Tai Ren, Ting-Jen R. Cheng, Tsui-Ling Hsu, Alice L. Yu, Chung-Yi Wu, and Chi-Huey Wong

Proc Natl Acad Sci U S A. 2013 February 12; 110(7): 2517–2522.


Toward Identifying the Effects of the Specific Components of Mindfulness-Based Stress Reduction on Biologic and Emotional Outcomes Among Older Adults

Gallegos AM, Hoerger M, Talbot NL, Krasner MS, Knight JM, Moynihan JA, Duberstein PR

J Altern Complement Med. 2013 Feb 5. [Epub ahead of print]


Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells

Aarntzen EH, Srinivas M, Bonetto F, Cruz LJ, Verdijk P, Schreibelt G, van de Rakt MW, Lesterhuis WJ, Van Riel M, Punt CJ, Adema GJ, Heerschap A, Figdor CG, Oyen WJ, de Vries IJ

Clin Cancer Res. 2013 Feb 4. [Epub ahead of print]


Prediction and identification of B-cell linear epitopes of hepatitis B e antigen

Yang J, Liu N, Zhang T, Zhao SP, Qiang L, Su BS, Kang AJ, Li ZF

Nan Fang Yi Ke Da Xue Xue Bao. 2013 Feb;33(2):253-7


Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats

Raleigh MD, Pravetoni M, Harris AC, Birnbaum AK, Pentel PR

J Pharmacol Exp Ther. 2013 Feb;344(2):397-406. doi: 10.1124/jpet.112.201194. Epub 2012 Dec 7


Neoantigen and tumor antigen-specific immunity transferred from immunized donors is detectable early after allogeneic transplantation in myeloma patients

Foglietta M, Neelapu SS, Kwak LW, Jiang Y, Nattamai D, Lee ST, Fowler DH, Sportes C, Gress RE, Steinberg SM, Vence LM, Radvanyi L, Dwyer KC, Qazilbash MH, Bryant RN, Bishop MR

Bone Marrow Transplant. 2013 Feb;48(2):269-77. doi: 10.1038/bmt.2012.132. Epub 2012 Jul 9


Developmental immunotoxicity of ethanol in an extended one-generation reproductive toxicity study.

Tonk EC, de Groot DM, Wolterbeek AP, Penninks AH, Waalkens-Berendsen ID, Piersma AH, van Loveren H

Arch Toxicol. 2013 Feb;87(2):323-35. doi: 10.1007/s00204-012-0940-1. Epub 2012 Sep 25


Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid.

Lauwerys BR, Hachulla E, Spertini F, Lazaro E, Jorgensen C, Mariette X, Haelterman E, Grouard-Vogel G, Fanget B, Dhellin O, Vandepapelière P, Houssiau FA

Arthritis Rheum. 2013 Feb;65(2):447-56. doi: 10.1002/art.37785


Preparation and characterization of monoclonal antibody specific for copper-chelate complex

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